Laboratory is certified to use autologous, allogeneic and xenogeneic cells for experimental and clinical purposes (including tissue engineering, progenitor cell based therapy, xenogeneic cell transplantation) according National Standard of Quality (Instructions No. 50-0303 and No. 55-0504, approved by Ministry of Health Care).

Our laboratory renders assistance in research concerned with receiving a degree in medicine. We also have possibility to transfer R&D results into clinical practice by conducting preclinical and clinical trials in the field of cell and tissue transplantation.

Current elaborations:

• Tissue and cell cultures from different sources.
• Isolation conditions and differentiation potential of human and animal progenitor and stem cells.
• Islet and neural progenitor cells for cellular transplantation in clinical trials.
• Apoptosis/proliferation in cell population.
• Transfection using AAV-vectors with protective genes.
• Biocompatible transplantable device supporting growth and differentiation of cells that enables monitoring of transplant both in vitro and in vivo, thus providing tracing of stem cells development, as well as differentiation of progenitor cells into desired cell types (islet cells, thyrocytes, chondrocytes and neural cells).
• Animal models; biochemical and functional methods; fluorescence microscopy; flow cytometry; testing of biomaterials, synthetic polymers and cell transplants.

Challenging elaborations:

• Use of autological chondrocytes and mesenchymal cells isolated from fat for therapy of cartilage defects.
• Use of biomaterials and composites for progenitor cells immobilization and cartilage tissue engineering.
• Use of fibroblasts and other cells that produce extracellular matrix for applications in medicine and cosmetology.